The five senses are gateways to our wellbeing and their decline is considered a significant public health challenge which is linked to multiple conditions that contribute significantly to morbidity and mortality. Modern technology, with its ubiquitous nature and fast data processing has the ability to leverage the power of the senses to transform our approach to day to day healthcare, with positive effects on our quality of life. Here, we introduce the idea of sensory-driven microinterventions for preventative, personalised healthcare. Microinterventions are targeted, timely, minimally invasive strategies that seamlessly integrate into our daily life. This idea harnesses human's sensory capabilities, leverages technological advances in sensory stimulation and real-time processing ability for sensing the senses. The collection of sensory data from our continuous interaction with technology - for example the tone of voice, gait movement, smart home behaviour - opens up a shift towards personalised technology-enabled, sensory-focused healthcare interventions, coupled with the potential of early detection and timely treatment of sensory deficits that can signal critical health insights, especially for neurodegenerative diseases such as Parkinson's disease.

There are various models proposed on how knowledge is generated in the human brain including the semantic networks model. Although this model has been widely studied and even computational models are presented, but, due to various limits and inefficiencies in the generation of different types of knowledge, its application is limited to semantic knowledge because of has been formed according to semantic memory and declarative knowledge and has many limits in explaining various procedural and conditional knowledge. Given the importance of providing an appropriate model for knowledge generation, especially in the areas of improving human cognitive functions or building intelligent machines, improving existing models in knowledge generation or providing more comprehensive models is of great importance. In the current study, based on the free energy principle of the brain, is the researchers proposed a model for generating three types of declarative, procedural, and conditional knowledge. While explaining different types of knowledge, this model is capable to compute and generate concepts from stimuli based on probabilistic mathematics and the action-perception process (active inference). The proposed model is unsupervised learning that can update itself using a combination of different stimuli as a generative model can generate new concepts of unsupervised received stimuli. In this model, the active inference process is used in the generation of procedural and conditional knowledge and the perception process is used to generate declarative knowledge.

Abstract-- Human physical function is governed by selfefficacy, the belief in one's motor capacity. In chronic pain patients, this capacity may remain reduced long after the damage causing the pain has been cured. Chronic pain alters body schema, affecting how patients perceive the dimension and pose of their bodies. We exploit this deficit using robotic manipulation technology and augmented sensory stimuli through virtual reality technology. We propose a sensory stimuli manipulation method aimed at modifying body schema to restore lost selfefficacy. Pharmaceuticals alone cannot cure this complex condition, which is influenced by biological, psychological, and social factors [1].

Significant plasticity in sensory cortical representations can be driven in mature animals either by behavioural tasks that pair sensory stimuli with reinforcement, or by electrophysiological experiments that pair sensory input with direct stimulation of neuromodulatory nuclei, but usually not by sensory stimuli presented alone. Biologically motivated theories of representational learning, however, have tended to focus on unsupervised mechanisms, which may play a significant role on evolutionary or devel- opmental timescales, but which neglect this essential role of reinforce- ment in adult plasticity. By contrast, theoretical reinforcement learning has generally dealt with the acquisition of optimal policies for action in an uncertain world, rather than with the concurrent shaping of sensory representations. This paper develops a framework for representational learning which builds on the relative success of unsupervised generative- modelling accounts of cortical encodings to incorporate the effects of reinforcement in a biologically plausible way.

In this series of Tales from the Dark Architecture articles I will be discussing some of the more extreme deep cognitive Artificial Intelligence designs that we are exploring on the pathway to Superintelligence. "Reality is a perception of trust fabricated by the human mind" We have approached a threshold in the design of Superintelligence. The issue before us is the nature of reality. Currently we are building AI machines to reflect our own human reality but what if they perceive far more than humans? Does human reality limit a Superintelligence and should a Superintelligence be free to experience a reality we humans can only contemplate but never experience? The truth is that advanced Cognitive AI systems not only perceive more of the natural world but they have the capacity to render more of the cognitively perceptive world than we humans can.

This study extends the mathematical model of emotion dimensions that we previously proposed (Yanagisawa, et al. 2019, Front Comput Neurosci) to consider perceived complexity as well as novelty, as a source of arousal potential. Berlyne's hedonic function of arousal potential (or the inverse U-shaped curve, the so-called Wundt curve) is assumed. We modeled the arousal potential as information contents to be processed in the brain after sensory stimuli are perceived (or recognized), which we termed sensory surprisal. We mathematically demonstrated that sensory surprisal represents free energy, and it is equivalent to a summation of information gain (or information from novelty) and perceived complexity (or information from complexity), which are the collative variables forming the arousal potential. We demonstrated empirical evidence with visual stimuli (profile shapes of butterfly) supporting the hypothesis that the summation of perceived novelty and complexity shapes the inverse U-shaped beauty function. We discussed the potential of free energy as a mathematical principle explaining emotion initiators.

This paper proposes a framework for the biological learning mechanism as a general learning system. The proposal is as follows. The bursting and tonic modes of firing patterns found in many neuron types in the brain correspond to two separate modes of information processing, with one mode resulting in awareness, and another mode being subliminal. In such a coding scheme, a neuron in bursting state codes for the highest level of perceptual abstraction representing a pattern of sensory stimuli, or volitional abstraction representing a pattern of muscle contraction sequences. Within the 50-250 ms minimum integration time of experience, the bursting neurons form synchrony ensembles to allow for binding of related percepts. The degree which different bursting neurons can be merged into the same synchrony ensemble depends on the underlying cortical connections that represent the degree of perceptual similarity. These synchrony ensembles compete for selective attention to remain active. The dominant synchrony ensemble triggers episodic memory recall in the hippocampus, while forming new episodic memory with current sensory stimuli, resulting in a stream of thoughts. Neuromodulation modulates both top-down selection of synchrony ensembles, and memory formation. Episodic memory stored in the hippocampus is transferred to semantic and procedural memory in the cortex during rapid eye movement sleep, by updating cortical neuron synaptic weights with spike timing dependent plasticity. With the update of synaptic weights, new neurons become bursting while previous bursting neurons become tonic, allowing bursting neurons to move up to a higher level of perceptual abstraction. Finally, the proposed learning mechanism is compared with the back-propagation algorithm used in deep neural networks, and a proposal of how the credit assignment problem can be addressed by the current proposal is presented.

Significant plasticity in sensory cortical representations can be driven in mature animals either by behavioural tasks that pair sensory stimuli with reinforcement, or by electrophysiological experiments that pair sensory input with direct stimulation of neuromodulatory nuclei, but usually not by sensory stimuli presented alone. Biologically motivated theories of representational learning, however, have tended to focus on unsupervised mechanisms, which may play a significant role on evolutionary or developmental timescales, but which neglect this essential role of reinforcement in adult plasticity. By contrast, theoretical reinforcement learning has generally dealt with the acquisition of optimal policies for action in an uncertain world, rather than with the concurrent shaping of sensory representations. This paper develops a framework for representational learning which builds on the relative success of unsupervised generativemodelling accounts of cortical encodings to incorporate the effects of reinforcement in a biologically plausible way.

Significant plasticity in sensory cortical representations can be driven in mature animals either by behavioural tasks that pair sensory stimuli with reinforcement, or by electrophysiological experiments that pair sensory input with direct stimulation of neuromodulatory nuclei, but usually not by sensory stimuli presented alone. Biologically motivated theories of representational learning, however, have tended to focus on unsupervised mechanisms, which may play a significant role on evolutionary or developmental timescales, but which neglect this essential role of reinforcement in adult plasticity. By contrast, theoretical reinforcement learning has generally dealt with the acquisition of optimal policies for action in an uncertain world, rather than with the concurrent shaping of sensory representations. This paper develops a framework for representational learning which builds on the relative success of unsupervised generativemodelling accounts of cortical encodings to incorporate the effects of reinforcement in a biologically plausible way.

Significant plasticity in sensory cortical representations can be driven in mature animals either by behavioural tasks that pair sensory stimuli with reinforcement, or by electrophysiological experiments that pair sensory input with direct stimulation of neuromodulatory nuclei, but usually not by sensory stimuli presented alone. Biologically motivated theories of representational learning, however, have tended to focus on unsupervised mechanisms, which may play a significant role on evolutionary or developmental timescales,but which neglect this essential role of reinforcement in adult plasticity. By contrast, theoretical reinforcement learning has generally dealt with the acquisition of optimal policies for action in an uncertain world, rather than with the concurrent shaping of sensory representations. This paper develops a framework for representational learning which builds on the relative success of unsupervised generativemodelling accountsof cortical encodings to incorporate the effects of reinforcement in a biologically plausible way.